The 2-Minute Rule for cees dekker
The 2-Minute Rule for cees dekker
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Nanotechnology provides A variety of chances to add to biology. In this article I'll existing illustrations where nanofabrication – the ability to make confined structures with dimensions at will – is utilized to look at the biophysics of one molecules and cells. I'll existing some illustrations from our lab:
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Nanofabrication of electrodes with sub-5 nm spacing for transport experiments on solitary molecules and metal clusters
2015, discovery that condensin is actually a extremely flexible protein framework; and very first detection of DNA knots utilizing nanopores
Direct immobilization of native yeast iso-one cytochrome c on bare gold: rapid electron relay to redox enzymes and zeptomole protein-movie voltammetry
MATLAB codes for details processing can be obtained at . Julia codes used for numerical simulation are offered at .
2000, discovery that nanotubes can carry incredible big latest densities; resolved the controversial situation of Digital transport by means of DNA molecules by measurements of insulating actions at the single molecule degree; and demonstration of the AFM system for single-molecule manipulation of nanotubes
In 1993, to be a young and eager associate professor at Delft College of Technology, I had originally centered the investigate efforts of my group on measuring the electrical conductance of an individual conducting-polymer molecule. Within just two years, we had made a tool in which just one wire of a phthalocyaninepolysiloxane polymer was linked involving two intently spaced metal nanoelectrodes.
Resolving the phase measurement in condensin-driven DNA loop extrusion identifies ATP binding because the move-making system
An built-in microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
Quite a few new phenomena had been discovered, and he and his exploration group recognized a leading posture On this field of investigation. Dekker and his study team found new physics of nanotubes together with explored the feasibility of molecular electronics. In 1998, they had been the main to create a transistor based on an individual nanotube molecule.
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It was an incredibly attention-grabbing time, throughout which I gained loads of assistance from Delft ceesdekker.net University of Technological know-how, exactly where I used to be a professor at enough time, And that i begun a number of collaborations with molecular biologists. That assisted me study lots.’